Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686479 | 0.90 | LMNA (0.54) | MEN1KMT2ABCHETYRACHE | |
| SCHEMBL8806213 | 0.87 | ADRA2A (0.57) | MEN1KMT2ACNR2CA12CA1 | |
| SCHEMBL30943709 | 0.87 | ADRA2A (0.57) | MEN1KMT2ACNR2CA12CA1 | |
| SCHEMBL2096168 | 0.86 | CA12 (0.56) | MEN1KMT2ABCHETYRACHE | |
| SCHEMBL131894 | 0.85 | BCHE (0.51) | MEN1KMT2ABCHETYRACHE | |
| SCHEMBL31722861 | 0.85 | LMNA (0.51) | MEN1KMT2ABCHETYRACHE | |
| SCHEMBL2516365 | 0.85 | MAPT (0.52) | GAABCHETYRACHELMNA | |
| SCHEMBL131893 | 0.84 | LMNA (0.49) | MEN1KMT2ABCHETYRACHE | |
| SCHEMBL7145569 | 0.84 | LMNA (0.46) | MEN1KMT2ABCHETYRACHE | |
| SCHEMBL11857411 | 0.83 | ACP3 (0.42) | MEN1KMT2AGAACNR2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385619-A2 | SYSTEM FOR THE SYNTHESIS OF SPATIALLY SEPARATED LIBRARIES OF COMPOUNDS AND METHODS FOR THE USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20030092064-A1 | Generation of preferential library; provide reaction aggregates, incubate each aggregate with chemical compound, monitor response at reaction aggregate | MILLENNIUM PHARMACEUTICALS, INC. | 2003-05-15 | — | — | US | disclosed |
| WO-2002081077-A2 | SYSTEM FOR THE SYNTHESIS OF SPATIALLY SEPARATED LIBRARIES OF COMPOUNDS AND METHODS FOR THE USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | WO | disclosed |