Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776831 | 0.81 | GRM8 (0.42) | GRM8GRM6GRM4L3MBTL1TDP1 | |
| SCHEMBL7113969 | 0.77 | GRM8 (0.49) | GRM8GRM6GRM4L3MBTL1TDP1 | |
| SCHEMBL7038633 | 0.74 | LMNA (0.46) | GRM8GRM6GRM4L3MBTL1TDP1 | |
| SCHEMBL27863450 | 0.71 | LMNA (0.56) | L3MBTL1TDP1KMT2APOLBLMNA | |
| SCHEMBL6741018 | 0.71 | GLO1 (0.45) | GRM8GRM6GRM4L3MBTL1TDP1 | |
| SCHEMBL10028335 | 0.70 | LMNA (0.46) | GRM8GRM6GRM4L3MBTL1TDP1 | |
| SCHEMBL15200988 | 0.70 | LMNA (0.58) | L3MBTL1TDP1KMT2APOLBLMNA | |
| SCHEMBL6550567 | 0.69 | GLO1 (0.51) | GRM8GRM6GRM4L3MBTL1TDP1 | |
| SCHEMBL11731878 | 0.69 | LMNA (0.53) | L3MBTL1TDP1KMT2APOLBLMNA | |
| SCHEMBL27853220 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483442-A2 | NOVEL CATALYTIC ACTIVITIES OF OXIDOREDUCTASES FOR OXIDATION AND/OR BLEACHING | Call, Krimhild (DE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003061550-A2 | NOVEL CATALYTIC ACTIVITIES OF OXIDOREDUCTASES FOR OXIDATION AND/OR BLEACHING | CALL, KRIMHILD (DE) | 2003-07-31 | — | — | WO | disclosed |
| US-3956312-A | ANTISECRETORY AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1976-05-11 | — | — | US | disclosed |