Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905708 | 0.89 | — | — | |
| Benzene SCHEMBL11545210 | 0.71 | LMNA (0.67) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL1761127 | 0.71 | FFAR3 (0.78) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL30925595 | 0.71 | FFAR3 (0.78) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL21273372 | 0.71 | FFAR3 (0.78) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL11152373 | 0.71 | LMNA (0.67) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL11307929 | 0.71 | LMNA (0.67) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL11765690 | 0.71 | LMNA (0.67) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL10771333 | 0.71 | LMNA (0.67) | FFAR3LCKFYNCA9CA1 | |
| Benzene SCHEMBL312284 | 0.71 | LMNA (0.67) | FFAR3LCKFYNCA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023310-B2 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2014-05-21 | — | — | EP | disclosed |
| EP-1023310-B1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6242591-B1 | Synthesis of sulfurized 2'-substituted oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | disclosed |