Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Malonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.82 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 3/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL28858100 | 0.96 | LDHA (0.75) | LDHASRRTSHRKDM4ELMNA | |
| Malonic Acid SCHEMBL28920112 | 0.96 | LDHA (0.75) | LDHASRRTSHRKDM4ELMNA | |
| Malonic Acid SCHEMBL23831 | 0.91 | LDHA (1.00) | LDHASRRTSHRKDM4ELMNA | |
| Malonic Acid SCHEMBL1332554 | 0.91 | — | — | |
| Malonic Acid SCHEMBL28221810 | 0.91 | LDHA (1.00) | LDHASRRTSHRKDM4ELMNA | |
| Malonic Acid SCHEMBL1332587 | 0.91 | — | — | |
| Malonic Acid SCHEMBL3358611 | 0.91 | — | — | |
| Malonic Acid SCHEMBL336 | 0.91 | — | — | |
| Malonic Acid SCHEMBL1332405 | 0.91 | — | — | |
| Malonic Acid SCHEMBL28435070 | 0.89 | LDHA (0.64) | LDHASRRTSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111945200-A | Environment-friendly zinc-nickel alloy coating passivation and zinc-nickel coating deplating method | 沈阳飞机工业（集团）有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-102876681-B | Nucleic acid aptamer for targeted medicament carrier | CHINESE ACAD INST CHEMISTRY | 2014-06-04 | — | — | CN | claimed |
| WO-2013090276-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | NOVOMER, INC. (US) | 2013-06-20 | — | — | WO | claimed |
| CN-102876681-A | Nucleic acid aptamer for targeted medicament carrier | CHINESE ACAD INST CHEMISTRY | 2013-01-16 | — | — | CN | claimed |
| CN-111148731-B | Fluorophenyl beta-hydroxyethylamine and its use in the treatment of hyperglycaemia | 阿托基公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118265691-A | Cyclohexylbeta-hydroxyalkylamines and their medical use | 阿托基公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118215652-A | Substituted hydroxymethyl pyrrolidines and medical uses thereof | 阿托基公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-116583980-A | Electrolyte composition for lithium metal battery | 索尔维公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115966766-A | Non-aqueous electrolyte and lithium ion battery | 惠州市豪鹏科技有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115692824-A | Lithium ion battery | 惠州市豪鹏科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115692847-A | Electrolyte and lithium ion battery | 惠州市豪鹏科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115663284-A | Electrolyte and lithium ion battery | 惠州市豪鹏科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-1306224-A | Iodonium salt used as potential acid provider | CIBA SPECIATY CHEMICALS HOLDIN (CH) | 2001-08-01 | — | — | CN | disclosed |
| US-6147129-A | Method for treating polyesters and, in particular, cleaning and decontaminating polyesters | THE COCA-COLA COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| WO-2000018830-A1 | METHOD FOR CLEANING AND DECONTAMINATING POLYESTERS | THE COCA-COLA COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |
| US-5473077-A | 4-aminopyrrolidine-2,4-substitude independently with carboxylic acid or 5-tetrazolyl for treating nervous system disorders and psychological disorders | ELI LILLY AND COMPANY (US) | 1995-12-05 | — | — | US | disclosed |
| CN-1094734-A | The fluoroelastomer of high resistance to polar solvent and alkali | AUSIMONT SPA (IT) | 1994-11-09 | — | — | CN | disclosed |
| US-5234819-A | Culture product of glucose with Erwinia | SHIONGI & CO., LTD. | 1993-08-10 | — | — | US | disclosed |
| CN-1072413-A | Amino acid derivative | HOFFMANN LA ROCHE (CH) | 1993-05-26 | — | — | CN | disclosed |
| WO-1990006775-A1 | A NOVEL NONPHOSPHOLIPID LIPOSOME COMPOSITION FOR SUSTAINED RELEASE OF DRUGS | LIPOSOME TECHNOLOGY, INC. (US) | 1990-06-28 | — | — | WO | disclosed |