SCHEMBL6551187

SCHEMBL6551187

CC(=O)n1cc([C@@]2(OP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@@H]2O)c2c(Cl)c(Br)ccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2804883 0.73
SCHEMBL3282414 0.70 NOTUM (0.41)
SCHEMBL7108455 0.69 NOTUM (0.34)
SCHEMBL32691742 0.67 NOTUM (0.36)
SCHEMBL6551234 0.66 NOTUM (0.37)
SCHEMBL25288671 0.64 AKR1C3 (0.42)
SCHEMBL5708142 0.62 CSNK2A1 (0.36)
SCHEMBL6238088 0.61
SCHEMBL5708137 0.59 NR4A2 (0.40)
SCHEMBL11213858 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970239-B1 DETECTION OF MICROBIAL METABOLITES BIOSYNTH AG (CH) 2004-12-08 EP disclosed
US-6068988-A DETECTING A PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN A SAMPLE BY CONTACTING WITH A CHROMOGENIC SUBSTRATE AND MONITORING FOR COLOR FORMATION BIOSYNTH AG (CH) 2000-05-30 US disclosed
US-6051391-A SUBSTRATE FOR ANALYSIS OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C WHICH INCLUDES 3-INDOXYL-MYO-INOSITOL-1-PHOSPHATE DERIVATIVE OR SALT; COLORIMETRIC ANALYSIS AND PLATING MEDIA BIOSYNTH AG (CH) 2000-04-18 US disclosed