SCHEMBL6551664

SCHEMBL6551664

CCC(C)(C(=O)O)N(C)c1ccccc1C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
RIPK1 Q13546 5/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36
MEN1 O00255 2/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
THRB P10828 1/20 0.34
BLM P54132 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
HIF1A Q16665 1/20 0.33
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTPN1 P18031 1/20 0.32
DRD2 P14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151140 0.76 KMT2A (0.44) CYP2C19CYP1A2CYP2D6RIPK1MEN1
SCHEMBL17536667 0.76 KMT2A (0.44) CYP2C19CYP1A2CYP2D6RIPK1MEN1
SCHEMBL6696630 0.71 LMNA (0.44) PTGDR2MEN1LMNAKMT2ATHRB
Acetic Acid SCHEMBL19133449 0.71 TSHR (0.47) PTGDR2MEN1LMNAKMT2ATHRB
SCHEMBL1427899 0.70 KMT2A (0.40) CYP2C19RIPK1PTGDR2MEN1LMNA
SCHEMBL7280841 0.70 LMNA (0.48) CYP2C19CYP1A2PTGDR2MEN1LMNA
SCHEMBL1169909 0.68 TDP1 (0.41) MEN1LMNAKMT2ATHRBBLM
SCHEMBL7293971 0.68 TDP1 (0.41) MEN1LMNAKMT2ATHRBBLM
SCHEMBL465195 0.68 KMT2A (0.50) PTGDR2MEN1LMNAKMT2ATHRB
SCHEMBL29354732 0.68 KMT2A (0.50) PTGDR2MEN1LMNAKMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
US-6306570-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6054260-A Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 2000-04-25 US disclosed
EP-0893731-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed