SCHEMBL1169909

SCHEMBL1169909

CCCCN(CCCC)c1ccccc1C=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 5/20 0.39
TSHR P16473 1/20 0.39
ALDH3A1 P30838 3/20 0.38
ALDH1A3 P47895 2/20 0.38
ELANE P08246 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TRIM24 O15164 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3362751 0.95 TDP1 (0.40) TDP1MEN1KMT2ALMNATHRB
SCHEMBL9746113 0.93 ALDH1A1 (0.41) TDP1MEN1KMT2ALMNATHRB
SCHEMBL9104204 0.93 ALDH1A1 (0.41) TDP1MEN1KMT2ALMNATHRB
SCHEMBL2832222 0.93 ALDH1A1 (0.41) TDP1MEN1KMT2ALMNATHRB
SCHEMBL4091793 0.89 ALDH1A1 (0.47) TDP1MEN1KMT2ALMNATHRB
SCHEMBL28401654 0.88 NR1H2 (0.44) TDP1MEN1KMT2ATSHRNPSR1
SCHEMBL7293971 0.86 TDP1 (0.41) TDP1MEN1KMT2ALMNATHRB
SCHEMBL2491664 0.85 TDP1 (0.37) TDP1MEN1KMT2ALMNAALDH1A1
SCHEMBL29954875 0.85 ALDH1A1 (0.34) TDP1MEN1KMT2ALMNATHRB
SCHEMBL5884328 0.83 CDK4 (0.42) TDP1MEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1575539-A1 DYE TABLETS Henkel Kommanditgesellschaft auf Aktien (DE) 2005-09-21 EP claimed
WO-2004058202-A1 DYE TABLETS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-15 WO claimed
EP-1381359-A1 AURONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-21 EP claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 WO claimed
US-20220407014-A1 ASYMMETRIC DONOR-ACCEPTOR MOLECULAR DYES THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE 2022-12-22 US disclosed
US-20220235075-A1 VOLTAGE SENSITIVE DYES AKITA INNOVATIONS LLC (US) 2022-07-28 US disclosed
US-11332484-B2 Voltage sensitive dyes AKITA INNOVATIONS LLC (US) 2022-05-17 US disclosed
US-20200071342-A1 VOLTAGE SENSITIVE DYES AKITA INNOVATIONS LLC (US) 2020-03-05 US disclosed
WO-2018217266-A9 VOLTAGE SENSITIVE DYES AKITA INNOVATIONS LLC (US) 2018-12-27 WO disclosed
WO-2018217266-A1 VOLTAGE SENSITIVE DYES AKITA INNOVATIONS LLC (US) 2018-11-29 WO disclosed
US-7888518-B2 Organic dye for recording layer and high density optical recording medium using the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-02-15 US disclosed
US-20100207078-A1 DEPROTECTION OF FUNCTIONAL GROUPS BY MULTI-PHOTON INDUCED ELECTRON TRANSFER THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2010-08-19 US disclosed
EP-1606045-A2 MIXING DEVICE Henkel Kommanditgesellschaft auf Aktien (DE) 2005-12-21 EP disclosed
WO-2004082818-A2 MIXING DEVICE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-09-30 WO disclosed
EP-1317243-A1 HAIR DYEING AGENTS CONTAINING INDIGO DERIVATIVES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-06-11 EP disclosed
EP-1192143-A1 RHODANINE DERIVATIVES FOR USE IN A METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS WARNER-LAMBERT COMPANY (US) 2002-04-03 EP disclosed
WO-2002022092-A1 HAIR DYEING AGENTS CONTAINING INDIGO DERIVATIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-03-21 WO disclosed
WO-2000076987-A1 RHODANINE DERIVATIVES FOR USE IN A METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS WARNER-LAMBERT COMPANY (US) 2000-12-21 WO disclosed
US-5517350-A Optical component based on Langmuir-Blodgett layers HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed
EP-0596325-A1 Optical element with Langmuir-Blodgett layers HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11332484-B2 Voltage sensitive dyes KCNN1, KCNN3, KCNN2 TDP1 2089/4885MEN1 1873/4885KMT2A 1252/4885
US-20100207078-A1 DEPROTECTION OF FUNCTIONAL GROUPS BY MULTI-PHOTON INDUCED ELECTRON TRANSFER GPX4, ERCC4, CYBA TDP1 1401/4885MEN1 4365/4885KMT2A 3722/4885
US-20220235075-A1 VOLTAGE SENSITIVE DYES KCNN1, KCNN3, KCNN2 TDP1 2089/4885MEN1 1873/4885KMT2A 1252/4885
US-20200071342-A1 VOLTAGE SENSITIVE DYES KCNN1, KCNN3, KCNN2 TDP1 2089/4885MEN1 1873/4885KMT2A 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.