SCHEMBL6551986

SCHEMBL6551986

COC1C(=O)NC(=O)N1Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.48
EHMT2 Q96KQ7 1/20 0.47
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44
MMP9 P14780 1/20 0.44
HPGD P15428 1/20 0.44
ELANE P08246 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
F2 P00734 1/20 0.41
PLG P00747 1/20 0.41
CTSG P08311 1/20 0.41
CMA1 P23946 1/20 0.41
CTRC Q99895 1/20 0.41
HCRTR1 O43613 1/20 0.41
HCRTR2 O43614 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3627524 0.83 EHMT2 (0.45) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL7498416 0.83 EHMT2 (0.45) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL9631715 0.83 EHMT2 (0.45) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL6551880 0.82 EHMT2 (0.44) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL6552002 0.81 EHMT2 (0.42) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL13297796 0.81 EHMT2 (0.49) HSD11B1EHMT2ELANEMEN1KMT2A
SCHEMBL6553109 0.80 HSD11B1 (0.43) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL6553757 0.79 MEN1 (0.43) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL10941894 0.78 EHMT2 (0.42) HSD11B1EHMT2MMP1MMP3MMP9
SCHEMBL9697471 0.78 EHMT2 (0.42) HSD11B1EHMT2ELANEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-7193080-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM, CO., LTD. (JP) 2007-03-20 US disclosed
EP-1070706-B1 Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones BAYER CHEMICALS AG (DE) 2004-02-18 EP disclosed
US-6365752-B1 REACTING GLYOXYLIC ACID AND AN N-SUBSTITUTED UREA IN AQUEOUS SOLUTION AND IN THE PRESENCE OF AN ACID CATALYST; EFFICIENCY; PURITY; NONTOXIC CHEMICAL INTERMEDIATES FOR DRUGS; INSECTICIDES; AMINO ACIDS AND TEXTILE ASSISTANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-04-02 US disclosed
EP-1070706-A1 Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones BAYER AG (DE) 2001-01-24 EP disclosed
US-4022620-A SILVER HALIDE, AMINE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-10 US disclosed