Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334405 | 0.94 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL6553658 | 0.94 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL9334414 | 0.94 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL6552002 | 0.91 | EHMT2 (0.42) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL3627524 | 0.85 | EHMT2 (0.45) | MEN1KMT2AALDH1A1CYP2C19EHMT2 | |
| SCHEMBL9631715 | 0.85 | EHMT2 (0.45) | MEN1KMT2AALDH1A1CYP2C19EHMT2 | |
| SCHEMBL7498416 | 0.85 | EHMT2 (0.45) | MEN1KMT2AALDH1A1CYP2C19EHMT2 | |
| SCHEMBL10941894 | 0.82 | EHMT2 (0.42) | MEN1KMT2AALOX12EHMT2MAPK1 | |
| SCHEMBL9697471 | 0.82 | EHMT2 (0.42) | MEN1KMT2AALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL6552399 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070706-B1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER CHEMICALS AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6365752-B1 | REACTING GLYOXYLIC ACID AND AN N-SUBSTITUTED UREA IN AQUEOUS SOLUTION AND IN THE PRESENCE OF AN ACID CATALYST; EFFICIENCY; PURITY; NONTOXIC CHEMICAL INTERMEDIATES FOR DRUGS; INSECTICIDES; AMINO ACIDS AND TEXTILE ASSISTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1070706-A1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER AG (DE) | 2001-01-24 | — | — | EP | disclosed |