Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553811 | 0.84 | CYP19A1 (0.47) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL7044616 | 0.76 | CNR1 (0.66) | CNR1 | |
| SCHEMBL6552035 | 0.76 | CNR1 (0.56) | CNR1 | |
| SCHEMBL6553446 | 0.75 | AR (0.51) | MEN1KMT2AFAAHTDP1ALDH1A1 | |
| SCHEMBL4075806 | 0.74 | CNR1 (0.57) | CNR1KDM4EFAAHALDH1A1MAPT | |
| SCHEMBL7042641 | 0.74 | DRD2 (0.53) | CNR1ALDH1A1NPSR1 | |
| SCHEMBL7041801 | 0.69 | CNR1 (0.56) | CNR1 | |
| SCHEMBL4085407 | 0.68 | CNR1 (0.66) | CNR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL4082543 | 0.68 | CNR1 (0.64) | CNR1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL4080145 | 0.68 | CNR1 (0.52) | CNR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |