Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8865735 | 0.84 | BCHE (0.65) | BCHEMAOBFFAR1SIGMAR1LTA4H | |
| Ammonia Solution, Strong SCHEMBL8865799 | 0.82 | BCHE (0.61) | BCHEMAOBSIGMAR1LTA4HMAOA | |
| Ammonia Solution, Strong SCHEMBL8866041 | 0.80 | BCHE (0.58) | BCHEMAOBSIGMAR1LTA4HMAOA | |
| Fumaric Acid SCHEMBL8866259 | 0.75 | ALDH1A1 (0.54) | BCHEMAOBFFAR1LTA4HALOX5 | |
| SCHEMBL3684825 | 0.74 | TAAR1 (0.50) | MAOBSIGMAR1MAOA | |
| SCHEMBL1042574 | 0.74 | BCHE (0.48) | BCHEMAOBFFAR1SIGMAR1 | |
| SCHEMBL21282920 | 0.73 | FFAR1 (0.42) | BCHEMAOBMRGPRX4FFAR1 | |
| SCHEMBL703 | 0.73 | LMNA (0.64) | BCHEMAOBFFAR1LTA4HMAOA | |
| Fumaric Acid SCHEMBL8976478 | 0.73 | ALDH1A1 (0.54) | BCHEMAOBFFAR1LTA4HALOX5 | |
| SCHEMBL8983689 | 0.72 | TAAR1 (0.56) | SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000051608-A1 | 3-THIENYL AND 3-FURANYL PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | claimed |
| EP-0980351-B1 | BENZYLAMINE AND PHENYLETHYLAMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6288277-B1 | DRUGS, ANTIARTHRITIC AGANTS, ANTIHISTAMINES FOR TREATMENT OF ASTHMA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-09-11 | — | — | US | disclosed |
| EP-0980351-A1 | NEW BENZYLAMINE AND PHENYLETHYLAMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049131-A1 | NEW BENZYLAMINE AND PHENYLETHYLAMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-11-05 | — | — | WO | disclosed |