Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553566 | 0.81 | L3MBTL1 (0.46) | MAPTCYP2C9L3MBTL1NPSR1NPC1 | |
| SCHEMBL6552161 | 0.76 | GAA (0.41) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL963694 | 0.74 | — | — | |
| SCHEMBL6552541 | 0.73 | ALDH1A1 (0.39) | NPSR1ALDH1A1GAALMNA | |
| SCHEMBL15881328 | 0.73 | L3MBTL1 (0.55) | MAPTCYP2C9L3MBTL1NPSR1NPC1 | |
| SCHEMBL14298343 | 0.72 | L3MBTL1 (0.54) | MAPTCYP2C9L3MBTL1NPSR1NPC1 | |
| SCHEMBL1673177 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28957211 | 0.70 | NPSR1 (0.47) | MAPTCYP2C9L3MBTL1NPSR1NPC1 | |
| SCHEMBL6861720 | 0.69 | NPSR1 (0.47) | MAPTCYP2C9L3MBTL1NPSR1NPC1 | |
| SCHEMBL6861724 | 0.69 | NPSR1 (0.47) | MAPTCYP2C9L3MBTL1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282628-B1 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2004-02-11 | — | — | EP | disclosed |
| EP-1282628-A2 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087898-A2 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2001-11-22 | — | — | WO | disclosed |