SCHEMBL6552183

SCHEMBL6552183

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1CN(C(=O)c2noc(C(CCCC3CCCCC3)CC(=O)O)n2)C1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 0.56
MMP2 P08253 5/20 0.56
MMP3 P08254 1/20 0.53
PDE4A P27815 1/20 0.49
PDE4B Q07343 1/20 0.49
PDE4C Q08493 1/20 0.49
PDE4D Q08499 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429284 1.00 BMP1 (0.56) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL6429405 0.91 BMP1 (0.70) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL27586685 0.88 BMP1 (0.64) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL6430136 0.88 BMP1 (0.64) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL27567269 0.85 BMP1 (0.59) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL27567472 0.84 BMP1 (0.64) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL6428683 0.84 BMP1 (0.64) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL6429363 0.83 BMP1 (0.60) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL6429077 0.83 BMP1 (0.67) BMP1MMP2MMP3PDE4APDE4B
SCHEMBL6428682 0.82 BMP1 (0.80) BMP1MMP2MMP3PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240152-B1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-08 EP disclosed