SCHEMBL6552225

SCHEMBL6552225

C[Si](O)(O)O.O=S(=O)(O)CS(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32
PDE4A P27815 1/20 0.32
LMNA P02545 1/20 0.32
SLC6A6 P31641 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34406 0.82
SCHEMBL1756114 0.79 CA2 (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19
Propane SCHEMBL28833415 0.79 CA5A (0.36) PTGS1PDE4ALMNASLC6A6CYP2C19
Methylamine SCHEMBL29008322 0.79 BLM (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
Phosphine SCHEMBL18006538 0.78 CA5A (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL17311994 0.78 CA5A (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL11351068 0.78 CA5A (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL14974326 0.78 CA5A (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL21404870 0.78 CA5A (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
Hydrochloric Acid SCHEMBL8715384 0.78 CA5A (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1089704-B1 TRICHOLOGICAL LOTION FOR TOPICAL USE GECOMWERT ANSTALT (LI) 2004-02-11 EP disclosed
US-6479059-B2 A COSMETIC COMPOSITION TO REACTIVATE THE PHYSIOLOGICAL GROWTH OF HAIR; COMPRISING A SYNERGISTIC MIXTURE OF CYSTEINE OR DERIVATIVES, LYSINE OR DERIVATIVES AND A GLYCOPROTEIN IN A CARRIER; SIDE EFFECT REDUCTION; THICKENING GROWTH GECOMWERT ANSTALT (LI) 2002-11-12 US disclosed
US-20010003583-A1 Trichological lotion for topical use GECOMWERT ANSTALT 2001-06-14 US disclosed
EP-1089704-A1 TRICHOLOGICAL LOTION FOR TOPICAL USE Gecomwert Anstalt (LI) 2001-04-11 EP disclosed
WO-1999066887-A1 TRICHOLOGICAL LOTION FOR TOPICAL USE GECOMWERT ANSTALT (LI) 1999-12-29 WO disclosed