Propomocarb

Propomocarb

SCHEMBL6552410

CCCOC(=O)NCCCN(C)C.CCCOC(=O)NCCCN(C)C.CCCOC(=O)NCCCN(C)C.OP(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.56
DNM1 Q05193 1/20 0.47
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
TLR2 O60603 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propomocarb SCHEMBL6552413 1.00 ACHE (0.56) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL21077 0.95 ACHE (0.61) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL17095085 0.93 ACHE (0.59) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL8437517 0.93 ACHE (0.59) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL68988 0.93 ACHE (0.59) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL28227333 0.92 ACHE (0.62) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL11597864 0.90 ACHE (0.56) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL1724451 0.90 ACHE (0.56) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL11598946 0.89 ACHE (0.54) ACHEDNM1CHRNB2CHRNB4CHRNA3
Propomocarb SCHEMBL11649993 0.89 ACHE (0.54) ACHEDNM1CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10767199-B2 Enzymatic preparation of Propamocarb EASTMAN CHEMICAL COMPANY (US) 2020-09-08 US disclosed
EP-3532630-B1 ENZYMATIC PREPARATION OF PROPAMOCARB EASTMAN CHEM CO (US) 2020-06-24 EP disclosed
US-20190300916-A1 ENZYMATIC PREPARATION OF PROPAMOCARB EASTMAN CHEMICAL COMPANY (US) 2019-10-03 US disclosed
EP-3532630-A1 ENZYMATIC PREPARATION OF PROPAMOCARB Eastman Chemical Company (US) 2019-09-04 EP disclosed
WO-2018081221-A1 ENZYMATIC PREPARATION OF PROPAMOCARB EASTMAN CHEMICAL COMPANY (US) 2018-05-03 WO disclosed
EP-1212332-B1 FUNGICIDES BAYER CROPSCIENCE GMBH (DE) 2004-02-11 EP disclosed
US-6639097-B1 Such as dimethyl-(3-(propoxycarbonylamino)propyl)-ammonium phosphate or phosphite; phycomycete diseases; phytophthora blights BAYER CROPSCIENCE GMBH (DE) 2003-10-28 US disclosed
EP-1212332-A1 FUNGICIDES Aventis CropScience GmbH (DE) 2002-06-12 EP disclosed
WO-2001021626-A1 FUNGICIDES AVENTIS CROPSCIENCE GMBH (DE) 2001-03-29 WO disclosed