Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL6552441

COc1c(C(=O)O)cc(C(=O)O)cc1S(=O)(=O)[O-].c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
ACLY P53396 4/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
PKM P14618 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MCL1 Q07820 1/20 0.37
RAD52 P43351 1/20 0.36
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
RAB9A P51151 1/20 0.35
TPMT P51580 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6154214 0.85 ALDH1A1 (0.39) ACLYALDH1A1HPGDKDM4ENPSR1
SCHEMBL6152656 0.78 BDKRB2 (0.39) ALDH1A1HPGDKDM4ENPSR1LMNA
SCHEMBL6152932 0.78 ALDH1A1 (0.35) ALDH1A1HPGDKDM4EPKMNPSR1
SCHEMBL6152497 0.76 ALDH1A1 (0.34) ALDH1A1HPGDKDM4EPKMNPSR1
SCHEMBL6419160 0.75 TPMT (0.44) ACLYALDH1A1HPGDKDM4EPKM
Tetraphenylphosphonium SCHEMBL3945860 0.72 LCK (0.47) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL4322338 0.71 TPMT (0.55) ALDH1A1HPGDKDM4EPKMLMNA
Tetraphenylphosphonium SCHEMBL6905021 0.69 F2 (0.42) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL3647091 0.68 IKBKB (0.50) ALDH1A1HPGDKDM4EHTTTPMT
SCHEMBL9456750 0.68 TPMT (0.39) ALDH1A1KDM4EPKMLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033244-B1 Biaxially oriented laminate polyester film TEIJIN LTD (JP) 2004-02-11 EP disclosed
US-6465075-B2 MULTILAYER; CONTAINING LUBRICANT TEIJIN LIMITED (JP) 2002-10-15 US disclosed
US-20010051257-A1 Biaxially oriented laminate polyester film KOBAYASHI IEYASU (JP) 2001-12-13 US disclosed
US-6319589-B1 MULTILAYER POLYESTER FILMS FIRST POLYESTER LAYER HAS A THICKNESS OF 0.3 TO 5 .MU.M, THE SECOND POLYESTER LAYER CONTAINS AN INERT FINE PARTICLE LUBRICANT TEIJIN LIMITED (JP) 2001-11-20 US disclosed
EP-1033244-A2 Biaxially oriented laminate polyester film TEIJIN LIMITED (JP) 2000-09-06 EP disclosed