Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552648 | 0.88 | KMT2A (0.43) | KMT2ALMNAKDM4EMAPTMAPK1 | |
| SCHEMBL6553586 | 0.86 | S1PR2 (0.34) | — | |
| SCHEMBL6553882 | 0.84 | KMT2A (0.41) | KMT2ACYP1A2CASP1LMNAHTT | |
| SCHEMBL30378441 | 0.79 | S1PR2 (0.31) | — | |
| SCHEMBL28209707 | 0.79 | S1PR2 (0.31) | — | |
| SCHEMBL6552493 | 0.79 | HTT (0.53) | KMT2ACYP1A2LMNAHTTKDM4E | |
| SCHEMBL1672474 | 0.74 | POLB (0.50) | KMT2ACYP1A2CASP1LMNAHTT | |
| SCHEMBL8349356 | 0.73 | KMT2A (0.54) | KMT2ACYP1A2CASP1LMNAKDM4E | |
| SCHEMBL12933406 | 0.73 | KMT2A (0.41) | KMT2ACYP1A2CASP1LMNAHTT | |
| SCHEMBL12963418 | 0.70 | KMT2A (0.50) | KMT2ACYP1A2CASP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282628-B1 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2004-02-11 | — | — | EP | disclosed |
| EP-1282628-A2 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087898-A2 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2001-11-22 | — | — | WO | disclosed |