SCHEMBL6553586

SCHEMBL6553586

O=P(Cl)(Cl)Nc1nc(Cl)cc(Cl)n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30378441 0.88 S1PR2 (0.31) S1PR2
SCHEMBL28209707 0.88 S1PR2 (0.31) S1PR2
SCHEMBL6552483 0.86 KMT2A (0.42)
SCHEMBL6552149 0.80 S1PR2 (0.33) S1PR2
SCHEMBL6552648 0.76 KMT2A (0.43)
SCHEMBL6553882 0.69 KMT2A (0.41)
SCHEMBL6552493 0.67 HTT (0.53)
SCHEMBL7035592 0.67 ATM (0.30)
SCHEMBL6553790 0.67 ALDH1A1 (0.39)
SCHEMBL28806162 0.65 S1PR2 (0.39) S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0329170-B1 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA (JP) 1995-06-21 EP claimed
US-4929729-A REACTION WITH PHOSPHOROUS OXYCHLORIDE, HYDROLYSIS, CHLORINATION ISHIHARA SANGYO KAISHA LTD. (JP) 1990-05-29 US claimed
EP-0329170-A2 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-08-23 EP claimed
EP-1282628-B1 N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS PIESTERITZ STICKSTOFF (DE) 2004-02-11 EP disclosed
EP-0329170-B1 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA (JP) 1995-06-21 EP disclosed
CN-1019575-B Production method of 2-amino-4, 6-dichloropyrimidine ISHIHARA SANGYO KAISHA (JP) 1992-12-23 CN disclosed
US-4929729-A REACTION WITH PHOSPHOROUS OXYCHLORIDE, HYDROLYSIS, CHLORINATION ISHIHARA SANGYO KAISHA LTD. (JP) 1990-05-29 US disclosed
US-4929729-A REACTION WITH PHOSPHOROUS OXYCHLORIDE, HYDROLYSIS, CHLORINATION ISHIHARA SANGYO KAISHA LTD. (JP) 1990-05-29 US disclosed
EP-0329170-A2 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-08-23 EP disclosed
EP-0329170-A2 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-08-23 EP disclosed