Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552161 | 0.87 | GAA (0.41) | KMT2ALMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL6552149 | 0.87 | S1PR2 (0.33) | — | |
| SCHEMBL6552483 | 0.84 | KMT2A (0.42) | KMT2ACYP1A2CASP1LMNAHTT | |
| SCHEMBL10932982 | 0.80 | CYP2D6 (0.31) | — | |
| SCHEMBL6553441 | 0.76 | TSHR (0.48) | KMT2ACYP1A2LMNAHTTMAPT | |
| SCHEMBL6552324 | 0.75 | TSHR (0.35) | KMT2ACYP1A2LMNAHTTMAPT | |
| SCHEMBL1672474 | 0.72 | POLB (0.50) | KMT2ACYP1A2CASP1LMNAHTT | |
| SCHEMBL31235463 | 0.71 | KMT2A (0.55) | KMT2ACYP1A2CASP1LMNAMAPT | |
| SCHEMBL6552648 | 0.71 | KMT2A (0.43) | KMT2ALMNAMAPTMAPK1KDM4E | |
| SCHEMBL10931726 | 0.70 | LMNA (0.38) | KMT2ACYP1A2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282628-B1 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2004-02-11 | — | — | EP | disclosed |