Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854460 | 1.00 | MAPT (0.36) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29750716 | 0.84 | CHRM1 (0.34) | OR51E2SLC6A9 | |
| SCHEMBL28376043 | 0.84 | CHRNB2 (0.37) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12534416 | 0.83 | TDP1 (0.36) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10207227 | 0.79 | OR51E2 (0.35) | OR51E2 | |
| SCHEMBL10207203 | 0.79 | OR51E2 (0.35) | OR51E2 | |
| SCHEMBL8948276 | 0.76 | OR51E2 (0.36) | OR51E2 | |
| SCHEMBL22645617 | 0.76 | OR51E2 (0.36) | OR51E2 | |
| SCHEMBL14930546 | 0.76 | CA12 (0.35) | OR51E2 | |
| SCHEMBL331728 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070045-B1 | METHODS FOR THE PREPARATION OF AN N-BIS- 2-(1,2-DICARBOXY-ETHOXY)-ETHYL]AMINE DERIVATIVE AND PRODUCTS OF THE METHODS AND THEIR USES | KEMIRA CHEMICALS OY (FI) | 2004-02-18 | — | — | EP | disclosed |
| EP-1070045-A1 | METHODS FOR THE PREPARATION OF AN N-BIS- 2-(1,2-DICARBOXY-ETHOXY)-ETHYL]AMINE DERIVATIVE AND PRODUCTS OF THE METHODS AND THEIR USES | KEMIRA CHEMICALS OY (FI) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999046234-A1 | METHODS FOR THE PREPARATION OF AN N-BIS-[2-(1,2-DICARBOXY-ETHOXY)-ETHYL]AMINE DERIVATIVE AND PRODUCTS OF THE METHODS AND THEIR USES | KEMIRA CHEMICALS OY (FI) | 1999-09-16 | — | — | WO | disclosed |