⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199040 | 1.00 | — | — | |
| SCHEMBL199041 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1903656 | 0.97 | OR51E2 (0.38) | — | |
| SCHEMBL14890159 | 0.80 | CHRNB2 (0.32) | — | |
| SCHEMBL28428696 | 0.79 | — | — | |
| SCHEMBL21621641 | 0.79 | CHRNB2 (0.36) | — | |
| SCHEMBL6562047 | 0.79 | CHRNB2 (0.36) | — | |
| SCHEMBL6135566 | 0.78 | — | — | |
| SCHEMBL25875074 | 0.78 | — | — | |
| SCHEMBL291712 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172273-A1 | CYCLOTETRAPEPTIDES WITH PRO-ANGIOGENIC PROPERTIES | GENETADI BIOTECH, S.L. (ES) | 2013-07-04 | — | — | US | disclosed |
| EP-2407478-A1 | New cyclotetrapeptides with pro-angiogenic properties | GENETADI Biotech, S.L. (ES) | 2012-01-18 | — | — | EP | disclosed |
| EP-0764648-B1 | Cephem derivatives and process for the preparation thereof | EISAI CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0333154-B1 | Process for the preparation of cephem derivatives | EISAI CO LTD (JP) | 1997-07-16 | — | — | EP | disclosed |
| EP-0764648-A1 | Cephem derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1997-03-26 | — | — | EP | disclosed |
| EP-0612751-A2 | Compounds for the preparation of cephem derivatives | Eisai Co., Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| CN-1022837-C | Process for preparation of cephem derivatives and intermediates therefor | EISAI CO LTD (JP) | 1993-11-24 | — | — | CN | disclosed |
| US-5128465-A | Containing thiadiazole ring and fluorine substitution | EISAI CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| CN-1036769-A | The method for preparing Cephem Derivative and intermediate thereof | EISAI CO LTD (JP) | 1989-11-01 | — | — | CN | disclosed |
| EP-0333154-A2 | Process for the preparation of cephem derivatives and intermediates therefor | Eisai Co., Ltd. (JP) | 1989-09-20 | — | — | EP | disclosed |