SCHEMBL6552745

SCHEMBL6552745

C=CC1OCC(C2COC(C=C)O2)O1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13822490 0.76
SCHEMBL23252686 0.74 TDP1 (0.30) TDP1
SCHEMBL14272687 0.74
SCHEMBL6677273 0.74
SCHEMBL4450588 0.74
SCHEMBL23260742 0.71
SCHEMBL13381087 0.69
SCHEMBL14539992 0.69
SCHEMBL9517594 0.69
SCHEMBL13381138 0.69 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822000-B2 ORTHOPEDIC IMPLANTS OR VEHICLES FOR THE SUSTAINED DELIVERY OF PHARMACEUTICAL, COSMETIC AND AGRICULTURAL AGENTS CONTAIN HYDROGEN BONDING GROUPS AND ALPHA-HYDROXY ACID-CONTAINING GROUPS AP PHARMA, INC. 2004-11-23 US disclosed
EP-1395626-A1 PEG-POE, PEG-POE-PEG, AND POE-PEG-POE BLOCK COPOLYMERS AP Pharma, Inc. (US) 2004-03-10 EP disclosed
EP-1385485-A1 BIOERODIBLE POLY(ORTHOESTERS) FROM DIOXOLANE-BASED DIKETENE ACETALS A.P. Pharma, Inc. (US) 2004-02-04 EP disclosed
US-20030152630-A1 PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers AP PHARMA, INC. 2003-08-14 US disclosed
US-20030130472-A1 Bioerodible poly (orthoesters)from dioxolane-based diketene acetals AP PHARMA, INC. 2003-07-10 US disclosed
US-6590059-B2 Orthopedic implants or vehicles for sustained delivery of pharmaceutical, cosmetic and agricultural agents AP PHARMA, INC. 2003-07-08 US disclosed
WO-2002092061-A1 BIORODIBLE POLY(ORTHOESTERS) FROM DIOXOLANE-BASED DIKETENE ACETALS A.P. PHARMA, INC. (US) 2002-11-21 WO disclosed
WO-2002092661-A1 PEG-POE, PEG-POE-PEG, AND POE-PEG-POE BLOCK COPOLYMERS AP PHARMA, INC. (US) 2002-11-21 WO disclosed
US-20020168336-A1 Bioerodible polyorthoesters from dioxolane-based diketene acetals HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) 2002-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030152630-A1 PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers POF1B, GNE, PAM TDP1 4449/4885ALDH1A1 2712/4885
US-20020168336-A1 Bioerodible polyorthoesters from dioxolane-based diketene acetals HAAO, HAO2, HAO1 TDP1 3448/4885ALDH1A1 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.