Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553077 | 0.85 | CA2 (0.46) | CA2CA1CA12CA9HTR2A | |
| SCHEMBL4427701 | 0.83 | PTPN1 (0.52) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL6541334 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TBXA2RTBXAS1HTR2AKCNH2 | |
| SCHEMBL6539934 | 0.78 | CA2 (0.48) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL6540455 | 0.77 | ALDH1A1 (0.50) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL3174253 | 0.76 | CA1 (0.53) | CA2CA1CA12CA9TBXA2R | |
| SCHEMBL917117 | 0.75 | CA1 (0.54) | CA2CA1CA12CA9TBXA2R | |
| SCHEMBL2187363 | 0.74 | CA1 (0.50) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL13220487 | 0.73 | PTPN1 (0.47) | CA2CA1ALDH1A1TBXA2RTBXAS1 | |
| SCHEMBL3608658 | 0.73 | EPHX2 (0.62) | CA2CA1CA12CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |