SCHEMBL6552870

SCHEMBL6552870

CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCCc1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MC4R P32245 5/20 0.53
CTSL P07711 2/20 0.49
NPY4R P50391 9/20 0.48
NPY5R Q15761 8/20 0.48
NPY1R P25929 7/20 0.48
NPY2R P49146 5/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MC3R P41968 1/20 0.48
MC1R Q01726 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552721 0.96 CTSL (0.54) MC4RCTSLNPY4RNPY5RNPY1R
SCHEMBL6552897 0.92 NPY4R (0.56) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL6551966 0.92 NPY4R (0.56) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL30029024 0.90 GNPAT (0.56) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL6551485 0.89 MC4R (0.57) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL6552855 0.89 MC4R (0.57) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL19656447 0.87 NPY4R (0.54) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL30712850 0.86 GNPAT (0.50) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL30712847 0.86 GNPAT (0.50) MC4RNPY4RNPY5RNPY1RNPY2R
SCHEMBL30712846 0.86 GNPAT (0.50) MC4RNPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040147567-A1 Control appetites; obesity; eating disorders TAISHO PHARMACEUTICALS CO., LTD. (JP) 2004-07-29 US claimed
EP-1388537-A1 ARGININE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD (JP) 2004-02-11 EP claimed
US-20040147567-A1 Control appetites; obesity; eating disorders TAISHO PHARMACEUTICALS CO., LTD. (JP) 2004-07-29 US disclosed
EP-1388537-A1 ARGININE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD (JP) 2004-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147567-A1 Control appetites; obesity; eating disorders MC4R, NPY4R, MC5R MC4R 1/4885CTSL 4034/4885NPY4R 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.