SCHEMBL6553092

SCHEMBL6553092

CC(=O)OC[C@@H](N)Cc1c[nH]cn1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ADRA1A P35348 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
MAP3K7 O43318 1/20 0.32
TAB1 Q15750 1/20 0.32
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22656748 1.00 KDM4E (0.33) KDM4EALDH1A1HPGDADRA1AHSD17B10
SCHEMBL14874483 0.89 MAP3K7 (0.30) MAP3K7TAB1
SCHEMBL25412095 0.86 MAP3K7 (0.30) MAP3K7TAB1
SCHEMBL29375642 0.79 MAP3K7 (0.32) MAP3K7TAB1
SCHEMBL6554654 0.79 MAPT (0.45) KDM4EALDH1A1
Histidine SCHEMBL16879895 0.78 SLC7A5 (0.38) ALDH1A1HSD17B10
Histidinol SCHEMBL28190716 0.78 ALPI (0.31)
SCHEMBL26762635 0.77 MAP3K7 (0.30) MAP3K7TAB1
SCHEMBL704416 0.77 S1PR2 (0.36)
SCHEMBL22367860 0.77 S1PR2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0688210-B1 USE OF CARNOSINE IN COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES BEIERSDORF AG (DE) 2004-02-25 EP claimed
EP-0688210-A1 USE OF CARNOSINE OR A COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES Beiersdorf Aktiengesellschaft (DE) 1995-12-27 EP claimed
WO-1994021245-A1 USE OF CARNOSINE OR A COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES BEIERSDORF AG (DE) 1994-09-29 WO claimed
US-11420943-B2 Peptide derivatives and therapeutic activity thereof FLAMMA S.P.A. (IT) 2022-08-23 US disclosed
EP-3732165-B1 PEPTIDE DERIVATIVES AND THERAPEUTIC ACTIVITY THEREOF FLAMMA SPA (IT) 2022-08-17 EP disclosed
US-20200361875-A1 PEPTIDE DERIVATIVES AND THERAPEUTIC ACTIVITY THEREOF FLAMMA S.P.A. (IT) 2020-11-19 US disclosed
EP-0688210-B1 USE OF CARNOSINE IN COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES BEIERSDORF AG (DE) 2004-02-25 EP disclosed
EP-0688210-A1 USE OF CARNOSINE OR A COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES Beiersdorf Aktiengesellschaft (DE) 1995-12-27 EP disclosed
WO-1994021245-A1 USE OF CARNOSINE OR A COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES BEIERSDORF AG (DE) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361875-A1 PEPTIDE DERIVATIVES AND THERAPEUTIC ACTIVITY THEREOF GPX4, VIP, GPX1 KDM4E 4773/4885ALDH1A1 1318/4885HPGD 183/4885
US-11420943-B2 Peptide derivatives and therapeutic activity thereof GPX4, VIP, GPX1 KDM4E 4773/4885ALDH1A1 1318/4885HPGD 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.