SCHEMBL29375642

SCHEMBL29375642

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAP3K7 O43318 1/20 0.32
TAB1 Q15750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21357734 0.91 CYP3A4 (0.32)
SCHEMBL2790558 0.87 NOS2 (0.33) MAP3K7TAB1
SCHEMBL1161686 0.86 CYP3A4 (0.31)
SCHEMBL14634845 0.85
SCHEMBL262238 0.85 ALDH1A1 (0.36) MAP3K7TAB1
SCHEMBL3846863 0.85 ALDH1A1 (0.36) MAP3K7TAB1
SCHEMBL833709 0.85 ALDH1A1 (0.36) MAP3K7TAB1
SCHEMBL9832443 0.85 SLC7A5 (0.34) MAP3K7TAB1
SCHEMBL6810243 0.85
SCHEMBL1994353 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508087-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE Genentech, Inc. (US) 2025-02-19 EP disclosed
EP-4508086-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE Genentech, Inc. (US) 2025-02-19 EP disclosed
CN-119384432-A Pharmaceutical compositions of therapeutic proteins and methods of use 基因泰克公司 2025-01-28 CN disclosed
US-20240408009-A1 CLINICAL FORMULATIONS OF ANTI-TIGIT ANTIBODIES GENENTECH INC (US) 2024-12-12 US disclosed
CN-119013299-A Mo Suni tobulab pharmaceutical compositions and methods of use 基因泰克公司 2024-11-22 CN disclosed
EP-4452320-A1 CLINICAL FORMULATIONS OF ANTI-TIGIT ANTIBODIES GENENTECH, INC. (US) 2024-10-30 EP disclosed
CN-118871131-A Clinical formulations of anti-TIGIT antibodies 基因泰克公司 2024-10-29 CN disclosed
US-20240209111-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE GENENTECH INC (US) 2024-06-27 US disclosed
US-11958906-B2 Pharmaceutical compositions of mosunetuzumab and methods of use GENENTECH, INC. (US) 2024-04-16 US disclosed
US-20230406930-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE GENENTECH, INC. 2023-12-21 US disclosed
WO-2023201299-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE GENENTECH, INC. (US) 2023-10-19 WO disclosed
WO-2023201291-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE GENENTECH, INC. (US) 2023-10-19 WO disclosed
US-20230331861-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE GENENTECH, INC. 2023-10-19 US disclosed
WO-2023122665-A1 CLINICAL FORMULATIONS OF ANTI-TIGIT ANTIBODIES GENENTECH, INC. (US) 2023-06-29 WO disclosed
US-20220125928-A1 COMPOSITIONS AND METHODS FOR STABILIZING PROTEIN-CONTAINING FORMULATIONS GENENTECH, INC. (US) 2022-04-28 US disclosed
US-20220064315-A1 MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE GENENTECH, INC. (US) 2022-03-03 US disclosed
EP-3946457-A1 COMPOSITIONS AND METHODS FOR STABILIZING PROTEIN-CONTAINING FORMULATIONS Genentech, Inc. (US) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230406930-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE SERPINA6, TTR, CHLSN MAP3K7 4206/4885TAB1 4597/4885
US-20220064315-A1 MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE HAVCR2, CD4, FCGR1A MAP3K7 3559/4885TAB1 2883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.