SCHEMBL29375642

SCHEMBL29375642

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MAP3K7 O43318 1/20 0.32
▸ TAB1 Q15750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21357734 0.91 CYP3A4 (0.32) —
SCHEMBL2790558 0.87 NOS2 (0.33) MAP3K7TAB1
SCHEMBL1161686 0.86 CYP3A4 (0.31) —
SCHEMBL14634845 0.85 — —
SCHEMBL833709 0.85 ALDH1A1 (0.36) MAP3K7TAB1
SCHEMBL262238 0.85 ALDH1A1 (0.36) MAP3K7TAB1
SCHEMBL3846863 0.85 ALDH1A1 (0.36) MAP3K7TAB1
SCHEMBL6810243 0.85 — —
SCHEMBL9832443 0.85 SLC7A5 (0.34) MAP3K7TAB1
SCHEMBL1994353 0.84 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508087-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE Genentech, Inc. (US) 2025-02-19 — — EP disclosed
EP-4508086-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE Genentech, Inc. (US) 2025-02-19 — — EP disclosed
CN-119384432-A Pharmaceutical compositions of therapeutic proteins and methods of use 基因泰克公司 2025-01-28 — — CN disclosed
US-20240408009-A1 CLINICAL FORMULATIONS OF ANTI-TIGIT ANTIBODIES GENENTECH INC (US) 2024-12-12 — — US disclosed
CN-119013299-A Mo Suni tobulab pharmaceutical compositions and methods of use 基因泰克公司 2024-11-22 — — CN disclosed
EP-4452320-A1 CLINICAL FORMULATIONS OF ANTI-TIGIT ANTIBODIES GENENTECH, INC. (US) 2024-10-30 — — EP disclosed
CN-118871131-A Clinical formulations of anti-TIGIT antibodies 基因泰克公司 2024-10-29 — — CN disclosed
US-20240209111-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE GENENTECH INC (US) 2024-06-27 — — US disclosed
US-11958906-B2 Pharmaceutical compositions of mosunetuzumab and methods of use GENENTECH, INC. (US) 2024-04-16 — — US disclosed
US-20230406930-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE GENENTECH, INC. 2023-12-21 — — US disclosed
WO-2023201299-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE GENENTECH, INC. (US) 2023-10-19 — — WO disclosed
WO-2023201291-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE GENENTECH, INC. (US) 2023-10-19 — — WO disclosed
US-20230331861-A1 PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE GENENTECH, INC. 2023-10-19 — — US disclosed
WO-2023122665-A1 CLINICAL FORMULATIONS OF ANTI-TIGIT ANTIBODIES GENENTECH, INC. (US) 2023-06-29 — — WO disclosed
US-20220125928-A1 COMPOSITIONS AND METHODS FOR STABILIZING PROTEIN-CONTAINING FORMULATIONS GENENTECH, INC. (US) 2022-04-28 — — US disclosed
US-20220064315-A1 MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE GENENTECH, INC. (US) 2022-03-03 — — US disclosed
EP-3946457-A1 COMPOSITIONS AND METHODS FOR STABILIZING PROTEIN-CONTAINING FORMULATIONS Genentech, Inc. (US) 2022-02-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230406930-A1 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE SERPINA6, TTR, CHLSN MAP3K7 4206/4885TAB1 4597/4885
US-20220064315-A1 MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE HAVCR2, CD4, FCGR1A MAP3K7 3559/4885TAB1 2883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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