Ether

Ether

SCHEMBL6553095

CCOCC.OCCC(Cl)Cl

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL16825634 0.83 TSHR (0.40) ALDH1A1
Ether SCHEMBL778289 0.80 ALDH1A1 (0.43) ALDH1A1
Ethane SCHEMBL7089366 0.80 THRB (0.35)
Ethane SCHEMBL8521430 0.80 THRB (0.35)
SCHEMBL1097 0.80
Ether SCHEMBL4944310 0.77 ALDH1A1 (0.45) ALDH1A1
Water SCHEMBL9657405 0.76
Ammonia Solution, Strong SCHEMBL4715986 0.76
Hydrochloric Acid SCHEMBL10326039 0.76
SCHEMBL28552387 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1018515-B1 Oligosaccharide, method for producing it and pharmaceutical composition containing it SEIKAGAKU KOGYO CO LTD (JP) 2004-02-18 EP disclosed
US-6642223-B2 A benzoazepin or benzodiazepin derivatives, shows excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as antagonist OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-11-04 US disclosed
US-6562954-B1 Oligosaccharide for use as tool in human therapeutics SEIKAGAKU CORPORATION (JP) 2003-05-13 US disclosed
EP-0757681-B1 CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-09-18 EP disclosed
EP-0858452-B1 THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS OTSUKA PHARMA CO LTD (JP) 2002-03-13 EP disclosed
US-6335327-B1 Benzoheterocyclic derivatives OTSUKA PHARMACEUTICALS CO., LTD. (JP) 2002-01-01 US disclosed
US-6140330-A USEFUL AS PROTEIN KINASE INHIBITOR; FOR TREATMENT OF AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS, SYSTEMIC LUPUS ERYTHEMATOSUS, MULTIPLE SCLEROSIS, PSORIASIS, ETC., VARIOUS ALLERGIC DISEASES SUCH AS CROHN'S DISEASE, ASTHMA OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed
US-6096735-A Benzoheterocyclic derivatives OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 2000-08-01 US disclosed
EP-1018515-A1 Oligosaccharide, method for producing it and pharmaceutical composition containing it SEIKAGAKU CORPORATION (JP) 2000-07-12 EP disclosed
EP-0605228-B1 Thiazolidinedione derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2000-03-01 EP disclosed
EP-0828731-A1 TRICYCLIC DIAZEPINES USEFUL AS GnRH RECEPTOR ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 1998-03-18 EP disclosed
WO-1998004536-A1 THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1998-02-05 WO disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
EP-0757681-A1 CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 1997-02-12 EP disclosed
WO-1996038438-A1 TRICYCLIC DIAZEPINES USEFUL AS GnRH RECEPTOR ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-12-05 WO disclosed
US-5489602-A HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-06 US disclosed
WO-1995029900-A1 CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-09 WO disclosed
EP-0605228-A1 Thiazolidinedione derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1994-07-06 EP disclosed
EP-0287150-B1 NOVEL 2 BETA-MORPHOLINO-ANDROSTANE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION AKZO N.V. (NL) 1992-08-19 EP disclosed
US-4894369-A Novel 2β-morpholino-androstane derivatives AKZO N.V. (NL) 1990-01-16 US disclosed