SCHEMBL6553173

SCHEMBL6553173

CC(C)(c1ccc(O)cc1)c1ccc(O)c(Br)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.73
ALOX12 P18054 2/20 0.73
ESR1 P03372 8/20 0.61
ESR2 Q92731 5/20 0.61
HSD17B10 Q99714 4/20 0.61
CYP3A4 P08684 3/20 0.61
HPGD P15428 3/20 0.61
TSHR P16473 2/20 0.61
AR P10275 1/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A4 P31645 1/20 0.61
HTR6 P50406 1/20 0.61
ESRRG P62508 1/20 0.61
SLC6A3 Q01959 1/20 0.61
ALDH1A1 P00352 4/20 0.53
TDP1 Q9NUW8 2/20 0.50
CASP1 P29466 1/20 0.50
RECQL P46063 1/20 0.50
HIF1A Q16665 1/20 0.50
KLF10 Q13118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352538 1.00 ALOX15 (0.73) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL29361821 0.92 ALOX15 (0.85) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL29378598 0.92 ALOX15 (0.85) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL121262 0.92 ALOX15 (0.85) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL9400834 0.87 ALOX15 (0.58) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL31757306 0.87 ALOX15 (0.71) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL11483498 0.87 ALOX15 (0.71) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL16285209 0.87 ALOX15 (0.71) ALOX15ALOX12ESR1ESR2HSD17B10
Propane SCHEMBL4424428 0.86 ALOX15 (0.76) ALOX15ALOX12ESR1ESR2HSD17B10
SCHEMBL4474163 0.85 ALOX15 (0.73) ALOX15ALOX12ESR1ESR2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
CN-108690215-A Intumescent system for flexible isolating foam 阿乐斯企业有限两合公司 2018-10-23 CN disclosed
CN-107922845-A The brominated flame retardants systems without antimony for textile 溴化合物有限公司 2018-04-17 CN disclosed
EP-3099738-A1 POLYOLEFIN COPOLYMERS AS COLOR ENHANCERS IN POLYAMIDES BASF SE (DE) 2016-12-07 EP disclosed
WO-2015110629-A1 POLYOLEFIN COPOLYMERS AS COLOR ENHANCERS IN POLYAMIDES BASF SE (DE) 2015-07-30 WO disclosed
WO-2014198756-A1 SEMI-AROMATIC COPOLYAMIDES BASED ON TEREPHTHALIC ACID AND ALIPHATIC DIAMINES BASF SE (DE) 2014-12-18 WO disclosed
EP-1086069-B1 A PROCESS FOR THE PREPARATION OF TETRABROMOBISPHENOL-A ALBEMARLE CORP (US) 2004-02-18 EP disclosed
EP-0822927-B1 A PROCESS FOR THE PREPARATION OF TETRABROMOBISPHENOL-A ALBEMARLE CORP (US) 2002-08-28 EP disclosed
US-6313355-B1 Process for the preparation of tetrabromobisphenol-A ALBEMARLE CORPORATION 2001-11-06 US disclosed
EP-0813513-B1 A PROCESS FOR THE PREPARATION OF TETRABROMOBISPHENOL-A ALBEMARLE CORP (US) 2001-10-31 EP disclosed
WO-1996033964-A1 A PROCESS FOR THE PREPARATION OF TETRABROMOBISPHENOL-A ALBEMARLE CORPORATION (US) 1996-10-31 WO disclosed
WO-1996027576-A1 A PROCESS FOR THE PREPARATION OF TETRABROMOBISPHENOL-A ALBEMARLE CORPORATION (US) 1996-09-12 WO disclosed
US-5527971-A FEEDING SOLUTION OF BISPHENOL A, WATER, WATER MISCIBLE SOLVENT TO HEATED REACTOR WITH BROMINE, PRECIPITATING PRODUCT, OXIDIZING PRODUCED HYDROGEN BROMIDE TO BROMINE ALBEMARLE CORPORATION (US) 1996-06-18 US disclosed
US-5283375-A Bromination bisphenol a in methanol solution ETHYL CORPORATION (US) 1994-02-01 US disclosed
US-5208389-A Contacting with treated water; heat treatment; flame retarders ETHYL CORPORATION (US) 1993-05-04 US disclosed
US-5107035-A Heat treating to reduce hydrobromic acid content ETHYL CORPORATION (US) 1992-04-21 US disclosed
US-4968769-A THERMOPLASTICS HAVING DIMENSIONAL STABILITY AT ELEVATED TEMPERATURES SHELL OIL COMPANY (US) 1990-11-06 US disclosed
EP-0016040-A1 BINARY AND TERNARY THERMOPLASTIC POLYCARBONATE ALLOYS GENERAL ELECTRIC COMPANY (US) 1980-10-01 EP disclosed
EP-0016040-A4 BINARY AND TERNARY THERMOPLASTIC POLYCARBONATE ALLOYS. GEN ELECTRIC (US) 1980-09-29 EP disclosed
WO-1980000027-A1 BINARY AND TERNARY THERMOPLASTIC POLYCARBONATE ALLOYS GEN ELECTRIC (US) 1980-01-10 WO disclosed