Propane

Propane

SCHEMBL4424428

CC(C)(c1ccc(O)c(Br)c1)c1ccc(O)c(Br)c1.CCC

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.76
ALOX12 P18054 2/20 0.76
ESR1 P03372 11/20 0.55
KLF10 Q13118 1/20 0.53
RORC P51449 1/20 0.53
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 2/20 0.52
RECQL P46063 2/20 0.52
CASP1 P29466 1/20 0.52
HIF1A Q16665 1/20 0.52
CHEK1 O14757 1/20 0.44
DAPK3 O43293 1/20 0.44
RET P07949 1/20 0.44
PDGFRB P09619 1/20 0.44
PIM1 P11309 1/20 0.44
PDGFRA P16234 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361821 0.94 ALOX15 (0.85) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL121262 0.94 ALOX15 (0.85) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL29378598 0.94 ALOX15 (0.85) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL4474163 0.86 ALOX15 (0.73) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL29466259 0.86 ALOX15 (1.00) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL29352538 0.86 ALOX15 (0.73) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL6553173 0.86 ALOX15 (0.73) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL6572582 0.86 ALOX15 (1.00) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL11483498 0.85 ALOX15 (0.71) ALOX15ALOX12ESR1KLF10RORC
SCHEMBL16285209 0.85 ALOX15 (0.71) ALOX15ALOX12ESR1KLF10RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021126796-A1 MOLDED ARTICLES COMPRISING A POST-CONSUMER RECYCLE POLYCARBONATE AND METHOD FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-24 WO disclosed
EP-3713765-A2 PANEL, INTEGRATED STRUCTURE, AND METHOD SABIC Global Technologies B.V. (NL) 2020-09-30 EP disclosed
WO-2019102349-A2 PANEL, INTEGRATED STRUCTURE, AND METHOD SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-05-31 WO disclosed
EP-2066727-A1 POLYCARBONATE-POLYSILOXANE COPOLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-06-10 EP disclosed
WO-2008042500-A1 POLYCARBONATE-POLYSILOXANE COPOLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-10 WO disclosed