Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053592 | 0.90 | — | — | |
| SCHEMBL3066603 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ALOX15TDP1TSHRMAPT | |
| SCHEMBL13464841 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRMAPT | |
| SCHEMBL21250221 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRMAPT | |
| SCHEMBL13464676 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRMAPT | |
| SCHEMBL13464870 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRMAPT | |
| SCHEMBL7794325 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL29941366 | 0.76 | ALDH1A1 (0.42) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL28617454 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHRMAPTLMNA | |
| SCHEMBL10424990 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149067-B1 | 7-ARYL-6(Z)HEPTATRIENOIC ACID RETINAMIDES AS APOPTOSIS INDUCING COMPOUNDS AND THEIR USE AS ANTI-CANCER AGENTS | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |