Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552324 | 0.85 | TSHR (0.35) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL6552493 | 0.85 | HTT (0.53) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL6552161 | 0.84 | GAA (0.41) | TSHRSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9847096 | 0.77 | HTT (0.54) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL6553882 | 0.76 | KMT2A (0.41) | SMN1; SMN2HTTALDH1A1LMNAMAPT | |
| SCHEMBL10508223 | 0.74 | HTT (0.56) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL10616011 | 0.73 | CYP1A2 (0.57) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL9129851 | 0.72 | CYP1A2 (0.61) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL16677950 | 0.72 | POLB (0.64) | TSHRSMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL25538376 | 0.72 | HTT (0.53) | TSHRSMN1; SMN2HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282628-B1 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2004-02-11 | — | — | EP | disclosed |