Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553441 | 0.85 | TSHR (0.48) | TSHRSMN1; SMN2HTTMAPTCYP1A2 | |
| SCHEMBL6552161 | 0.82 | GAA (0.41) | TSHRSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL6553882 | 0.75 | KMT2A (0.41) | SMN1; SMN2HTTMAPTCYP1A2ALDH1A1 | |
| SCHEMBL10936663 | 0.71 | ALDH1A1 (0.40) | TSHRHTTMAPTALDH1A1LMNA | |
| SCHEMBL6552493 | 0.70 | HTT (0.53) | TSHRSMN1; SMN2HTTMAPTCYP1A2 | |
| SCHEMBL6552139 | 0.66 | MAPT (0.46) | SMN1; SMN2MAPTCYP2C9ALDH1A1LMNA | |
| SCHEMBL10935113 | 0.65 | — | — | |
| SCHEMBL10937914 | 0.65 | — | — | |
| SCHEMBL23646019 | 0.64 | SMN1; SMN2 (0.41) | TSHRSMN1; SMN2HTTMAPTCYP1A2 | |
| SCHEMBL6552149 | 0.64 | S1PR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282628-B1 | N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-4518413-A | Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |