SCHEMBL6553580

SCHEMBL6553580

C[C](C)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CES1 P23141 3/20 0.48
CASP3 P42574 1/20 0.46
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.43
ASAH1 Q13510 1/20 0.43
POLB P06746 1/20 0.43
SCN2A Q99250 1/20 0.43
LMNA P02545 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TTR P02766 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887161 0.83 CES1 (0.62) ALDH1A1CES1CASP3CA9CA12
SCHEMBL4863625 0.81 ALDH1A1 (0.47) ALDH1A1CES1CASP3CA9CA12
SCHEMBL28277804 0.81 ALDH1A1 (0.47) ALDH1A1CES1CASP3CA9CA12
SCHEMBL8732506 0.81 ALDH1A1 (0.57) ALDH1A1CES1CASP3CA9CA12
SCHEMBL21855119 0.79 CA12 (0.52) ALDH1A1CES1CASP3CA9CA12
SCHEMBL1457554 0.78 CA9 (0.51) ALDH1A1CES1CASP3CA9CA12
SCHEMBL7335823 0.78 CES1 (0.66) ALDH1A1CES1CA9CA12ASAH1
SCHEMBL10865680 0.78 ALDH1A1 (0.44) ALDH1A1CES1CASP3CA9CA12
SCHEMBL330062 0.78 ALDH1A1 (0.53) ALDH1A1CES1CASP3CA9CA12
SCHEMBL238006 0.77 CA12 (0.50) ALDH1A1CES1CASP3CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016653-B1 Preparation of high-dye yield couplers and intermediates useful therein EASTMAN KODAK CO (US) 2004-02-25 EP disclosed
US-6620580-B2 Photographic element comprising a support bearing a blue light sensitive record containing at least three layers having different levels of light sensitivity arranged in the order slowest to fastest with the slowest layer closest to the EASTMAN KODAK COMPANY 2003-09-16 US disclosed
US-20030143498-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY 2003-07-31 US disclosed
EP-1004932-B1 Photographic and imaging elements including biaxially oriented polyolefin sheets EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
US-6569612-B1 Photographic paper containing photosensitive silver halide emulsion layers, binders, azo/methine dyes and dye developers used for printing or scanning images EASTMAN KODAK COMPANY 2003-05-27 US disclosed
EP-1312978-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY (US) 2003-05-21 EP disclosed
EP-1291715-A2 Photographic element containing a high-dye-yield coupler for producing a yellow hue EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
EP-0825488-B1 Coupler set for silver halide color imaging EASTMAN KODAK CO (US) 2002-10-30 EP disclosed
US-6465164-B1 COMPRISING AT LEAST FOUR SEPARATELY SENSITIZED LIGHT-SENSITIVE SILVER HALIDE EMULSION LAYERS CONTAINING, IN ADDITION TO THE CONVENTIONAL CYAN, MAGENTA, AND YELLOW DYE-FORMING LAYERS, A FOURTH IMAGE DYE-FORMING LAYER COMPRISING A COUPLER EASTMAN KODAK COMPANY 2002-10-15 US disclosed
US-6406837-B1 FORMING IMAGE ON TRANSPARENT SHEET AND PHOTOSENSITIVE DYE ON ONE SIDE OF SHEET; EXPOSURE TO ACTINIC RADIATION EASTMAN KODAK COMPANY 2002-06-18 US disclosed
EP-0107112-A2 Silver halide color photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1984-05-02 EP disclosed
EP-0101621-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-02-29 EP disclosed
EP-0096873-A2 Silver halide color photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1983-12-28 EP disclosed
US-4293691-A Method for preparing magenta couplers having thioether groups FUJI PHOTO FILM CO., LTD. (JP) 1981-10-06 US disclosed
US-4283486-A DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1981-08-11 US disclosed
US-4266019-A HETEROCYCLIC SUBSTITUTED AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1981-05-05 US disclosed
US-4146396-A TWO EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1979-03-27 US disclosed
US-4022620-A SILVER HALIDE, AMINE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-10 US disclosed
US-4012259-A DICARBONYL METHYLENE GROUP ON A 2,5-DIOXO-1-IMIDAZOLIDINE IS A YELLOW COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-03-15 US disclosed
US-3990896-A YELLOW COLOR FORMING COUPLERS WITH 5-ALKYLIDINE-3-HYDANTOINYL GROUPS FUJI PHOTO FILM CO., LTD. (JA) 1976-11-09 US disclosed