SCHEMBL65536

SCHEMBL65536

CC(=O)C(O)CCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.64
KDM4A O75164 2/20 0.64
KDM4C Q9H3R0 2/20 0.64
KDM2A Q9Y2K7 2/20 0.64
TET3 O43151 1/20 0.64
GABRP O00591 2/20 0.48
GABRD O14764 2/20 0.48
GABRA1 P14867 2/20 0.48
GABRB1 P18505 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRA3 P34903 2/20 0.48
GABRA2 P47869 2/20 0.48
GABRB2 P47870 2/20 0.48
GABRA4 P48169 2/20 0.48
GABRE P78334 2/20 0.48
GABRA6 Q16445 2/20 0.48
GABRG1 Q8N1C3 2/20 0.48
GABRG3 Q99928 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19633036 1.00 TET2 (0.64) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL10044876 1.00 TET2 (0.64) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL29011390 0.85 TET2 (0.46) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL10044873 0.85 TET2 (0.46) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL27557387 0.81 FFAR4 (0.57) LMNAFFAR4FFAR1
SCHEMBL14802254 0.81 TET2 (0.48) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL10308721 0.81 ALDH1A1 (0.47) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL13967809 0.80 TET2 (0.58) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL10044872 0.80 TET2 (0.41) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL17378384 0.80 TET2 (0.35) TET2KDM4AKDM4CKDM2ATET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909905-A Construction method and application of optimized L-isoleucine production strain 元素驱动(杭州)生物科技有限公司 2024-11-08 CN claimed
CN-118685334-A Engineering bacterium for producing L-isoleucine and construction method and application thereof 中国科学院微生物研究所 2024-09-24 CN claimed
CN-117757651-B Method for improving L-isoleucine yield by optimizing threonine dehydratase or deaminase expression 元素驱动(杭州)生物科技有限公司 2024-09-17 CN claimed
CN-118240726-A Escherichia coli engineering bacteria utilizing sucrose or molasses and method for producing branched chain amino acid by fermentation of escherichia coli engineering bacteria 元素驱动(杭州)生物科技有限公司 2024-06-25 CN claimed
CN-118222648-A Method for producing L-valine and L-isoleucine by using recovered thalli 元素驱动(杭州)生物科技有限公司 2024-06-21 CN claimed
CN-117757651-A Method for improving L-isoleucine yield by optimizing threonine dehydratase or deaminase expression 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117757705-A Construction and application of genetic engineering strain capable of realizing co-production of branched-chain amino acid 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117757704-A Method for improving yield of Branched Chain Amino Acid (BCAA) and strain construction 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117757860-A Application of threonine extraction waste liquid and/or fermentation liquid in fermentation production of L-isoleucine and fermentation method 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117546851-A Herbicidal compositions containing uracil compounds of carboxylate fragments and uses thereof 江苏中旗科技股份有限公司 2024-02-13 CN claimed
US-20050014647-A1 Method and composition for determining resistance to an acetohydroxy-acid synthase inhibitor BASF AKTIENGESELLSCHAFT (DE) 2005-01-20 US claimed
EP-1417331-A2 IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR BASF AKTIENGESELLSCHAFT (DE) 2004-05-12 EP claimed
US-20030180929-A1 Structure-based designed herbicide resistant products AMERICAN HOME PRODUCTS CORPORATION 2003-09-25 US claimed
WO-2003014379-A2 IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR BASF AKTIENGESELLSCHAFT (DE) 2003-02-20 WO claimed
EP-0821729-A4 STRUCTURE-BASED DESIGNED HERBICIDE RESISTANT PRODUCTS AMERICAN CYANAMID CO (US) 1999-12-08 EP claimed
US-RE36175-E TREATING SUSCEPTIBLE PLANT WITH COMPOUND AND KETOL-ACID REDUCTOISOMERASE INHIBITOR, TREATING SECOND PLANT WITH INHIBITOR ALONE, MEASURING ACETOLACTATE AND ACETOHYDROXYBUTYRATE FORMED AMERICAN CYANAMID COMPANY (US) 1999-03-30 US claimed
US-5853973-A Structure based designed herbicide resistant products AMERICAN CYANAMID COMPANY (US) 1998-12-29 US claimed
EP-0821729-A1 STRUCTURE-BASED DESIGNED HERBICIDE RESISTANT PRODUCTS AMERICAN CYANAMID COMPANY (US) 1998-02-04 EP claimed
WO-1996033270-A1 STRUCTURE-BASED DESIGNED HERBICIDE RESISTANT PRODUCTS AMERICAN CYANAMID COMPANY (US) 1996-10-24 WO claimed
US-5356789-A For plants; quantitative, colorimetric analysis AMERICAN CYANAMID COMPANY (US) 1994-10-18 US claimed