Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.64 |
| ▸ | KDM4A | O75164 | 2/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.64 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.64 |
| ▸ | TET3 | O43151 | 1/20 | 0.64 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65536 | 1.00 | TET2 (0.64) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL10044876 | 1.00 | TET2 (0.64) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL29011390 | 0.85 | TET2 (0.46) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL10044873 | 0.85 | TET2 (0.46) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL27557387 | 0.81 | FFAR4 (0.57) | LMNAFFAR4FFAR1 | |
| SCHEMBL14802254 | 0.81 | TET2 (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL10308721 | 0.81 | ALDH1A1 (0.47) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL13967809 | 0.80 | TET2 (0.58) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL10044872 | 0.80 | TET2 (0.41) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL17378384 | 0.80 | TET2 (0.35) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144845-A1 | Alpha-Ketobutyrate, 2-Hydroxybutyrate, and Alpha-Ketoglutarate for Stimulating Hair Growth | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| US-20170333373-A1 | Glutarate Compounds for Treating Ischemia-Reperfusion Injuries | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333373-A1 | Glutarate Compounds for Treating Ischemia-Reperfusion Injuries | GCDH, OGDH, GLS | TET2 2614/4885KDM4A 1579/4885KDM4C 1960/4885 |
| US-20230144845-A1 | Alpha-Ketobutyrate, 2-Hydroxybutyrate, and Alpha-Ketoglutarate for Stimulating Hair Growth | HOGA1, GCDH, LDHB | TET2 1056/4885KDM4A 1352/4885KDM4C 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.