Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553961 | 0.92 | LMNA (0.36) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL5691797 | 0.91 | LMNA (0.39) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL7949966 | 0.91 | LMNA (0.39) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL6699195 | 0.89 | CYP4F2 (0.44) | CYP4F2CYP4A11BAZ2BBAZ2ALMNA | |
| SCHEMBL2968009 | 0.89 | LMNA (0.36) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL2964906 | 0.89 | TDP1 (0.36) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL2966447 | 0.89 | LMNA (0.36) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL6552716 | 0.89 | LMNA (0.36) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL2961429 | 0.89 | TDP1 (0.36) | LMNATHRBCTSBTDP1NOTUM | |
| SCHEMBL6552521 | 0.88 | CYP4F2 (0.33) | CYP4F2CYP4A11BAZ2BBAZ2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436680-B1 | HETEROCYCLIC COMPOUNDS | CIBA GEIGY AG (CH) | 1994-09-07 | — | — | EP | claimed |
| EP-1206185-B1 | COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1206185-A1 | COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS | Aventis CropScience GmbH (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001008487-A1 | COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-08 | — | — | WO | disclosed |
| US-5183492-A | Herbicides as enol ethers | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |