Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 4/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403520 | 0.90 | POLB (0.43) | NPY4RNPY1RNPY2RNPY5RF10 | |
| SCHEMBL3847129 | 0.90 | POLB (0.43) | NPY4RNPY1RNPY2RNPY5RF10 | |
| Hydrochloric Acid SCHEMBL11211338 | 0.89 | HDAC3 (0.43) | NPY4RNPY1RNPY2RNPY5RTERT | |
| Hydrochloric Acid SCHEMBL11106339 | 0.89 | HDAC3 (0.43) | NPY4RNPY1RNPY2RNPY5RTERT | |
| Hydrochloric Acid SCHEMBL9618470 | 0.88 | POLB (0.42) | NPY4RNPY1RNPY2RNPY5RF10 | |
| SCHEMBL8416482 | 0.83 | HDAC1 (0.47) | PRSS1 | |
| Bromide SCHEMBL11101365 | 0.82 | HDAC1 (0.46) | PRSS1 | |
| SCHEMBL1735090 | 0.79 | PRSS1 (0.42) | ITGB3ITGA2BTPSAB1ST14F10 | |
| Arginine SCHEMBL4606883 | 0.78 | F10 (0.44) | ITGB3ITGA2BTPSAB1F10PRSS1 | |
| Arginine SCHEMBL4606882 | 0.78 | F10 (0.44) | ITGB3ITGA2BTPSAB1F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485345-A2 | UROKINASE INHIBITORS, PRODUCTION AND USE THEREOF | Curacyte AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003076391-A2 | UROKINASE INHIBITORS, PRODUCTION AND USE THEREOF | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | disclosed |