Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553757 | 0.81 | MEN1 (0.43) | ALDH1A1CYP3A4MEN1KMT2AL3MBTL1 | |
| SCHEMBL6553109 | 0.79 | HSD11B1 (0.43) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL9334405 | 0.79 | MEN1 (0.44) | ALDH1A1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL6553658 | 0.79 | MEN1 (0.44) | ALDH1A1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL9334414 | 0.79 | MEN1 (0.44) | ALDH1A1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL6552002 | 0.78 | EHMT2 (0.42) | ALDH1A1CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL7498416 | 0.78 | EHMT2 (0.45) | ALDH1A1MEN1KMT2ACYP2C19EHMT2 | |
| SCHEMBL9631715 | 0.78 | EHMT2 (0.45) | ALDH1A1MEN1KMT2ACYP2C19EHMT2 | |
| SCHEMBL3627524 | 0.78 | EHMT2 (0.45) | ALDH1A1MEN1KMT2ACYP2C19EHMT2 | |
| SCHEMBL6551986 | 0.72 | HSD11B1 (0.48) | ALDH1A1MEN1KMT2AEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070706-B1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER CHEMICALS AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6365752-B1 | REACTING GLYOXYLIC ACID AND AN N-SUBSTITUTED UREA IN AQUEOUS SOLUTION AND IN THE PRESENCE OF AN ACID CATALYST; EFFICIENCY; PURITY; NONTOXIC CHEMICAL INTERMEDIATES FOR DRUGS; INSECTICIDES; AMINO ACIDS AND TEXTILE ASSISTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1070706-A1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER AG (DE) | 2001-01-24 | — | — | EP | disclosed |