SCHEMBL6553785

SCHEMBL6553785

CCOC(=O)C(C)(C)OC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
BAZ2B Q9UIF8 1/20 0.34
BAZ2A Q9UIF9 1/20 0.34
PPARA Q07869 6/20 0.34
PPARD Q03181 5/20 0.34
PPARG P37231 3/20 0.34
CTSB P07858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NOTUM Q6P988 2/20 0.33
ABCB11 O95342 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
HTR2A P28223 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9589477 0.93 CYP4F2 (0.33) CYP4F2CYP4A11BAZ2BBAZ2APPARA
SCHEMBL14036918 0.93 ALDH1A1 (0.32) PPARAPPARDPPARGCTSBTDP1
SCHEMBL6553619 0.91 CYP4F2 (0.33) CYP4F2CYP4A11BAZ2BBAZ2APPARA
SCHEMBL9603218 0.91 CYP4F2 (0.34) CYP4F2CYP4A11BAZ2BBAZ2APPARA
SCHEMBL9350533 0.90 CTSB (0.33) PPARAPPARDPPARGCTSBTDP1
SCHEMBL6553913 0.90 MEN1 (0.35) PPARAPPARDPPARGCTSBTDP1
Butafenacil SCHEMBL29482232 0.89 XPA (0.34) PPARAPPARDPPARGMAPK1LMNA
Butafenacil SCHEMBL39148 0.89 XPA (0.34) PPARAPPARDPPARGMAPK1LMNA
SCHEMBL6699195 0.89 CYP4F2 (0.44) CYP4F2CYP4A11BAZ2BBAZ2ACTSB
SCHEMBL2969894 0.88 TDP1 (0.34) PPARAPPARDPPARGCTSBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436680-B1 HETEROCYCLIC COMPOUNDS CIBA GEIGY AG (CH) 1994-09-07 EP claimed
EP-1206185-B1 COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS BAYER CROPSCIENCE GMBH (DE) 2004-02-18 EP disclosed
US-5183492-A Herbicides as enol ethers CIBA-GEIGY CORPORATION (US) 1993-02-02 US disclosed