Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634800 | 0.75 | MLYCD (0.40) | OXTRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL3634187 | 0.74 | KMT2A (0.43) | OXTRALDH1A1GAAMAPTNPC1 | |
| SCHEMBL1097728 | 0.74 | MLYCD (0.39) | OXTRMAPTNPC1RAB9AHTT | |
| SCHEMBL791057 | 0.73 | HTT (0.51) | ALDH1A1HPGDGAAMAPTNPC1 | |
| SCHEMBL6552652 | 0.72 | ESR1 (0.35) | OXTRALDH1A1HPGDHTTBRAF | |
| SCHEMBL6541375 | 0.71 | KMT2A (0.46) | ALDH1A1GAANPC1LMNARAB9A | |
| SCHEMBL1097623 | 0.70 | MLYCD (0.39) | OXTRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL27863750 | 0.69 | HDAC1 (0.38) | OXTRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9904990 | 0.69 | MMP2 (0.46) | ALDH1A1MMP2MMP9GAAMAPT | |
| SCHEMBL4002016 | 0.68 | MLYCD (0.43) | ALDH1A1MAPTNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |