Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554097 | 0.90 | HDAC1 (0.41) | PTGS2HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL6540218 | 0.87 | SLC6A9 (0.46) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL6539902 | 0.83 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL6810353 | 0.82 | HDAC1 (0.46) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL6541405 | 0.81 | LPAR1 (0.54) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL9823156 | 0.81 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL6802456 | 0.80 | LPAR1 (0.47) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL6540935 | 0.80 | LPAR1 (0.48) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL1798901 | 0.78 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL3695642 | 0.78 | HDAC1 (0.55) | HDAC1HDAC3HDAC2NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |