SCHEMBL6554113

SCHEMBL6554113

Cc1cc(O)n2nc(C(=O)O)nc2n1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.65
MEN1 O00255 2/20 0.65
ALDH1A1 P00352 6/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
CASP1 P29466 1/20 0.40
MAPT P10636 1/20 0.40
USP2 O75604 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10461118 0.84 KMT2A (0.67) KMT2AMEN1ALDH1A1SMN1; SMN2LMNA
SCHEMBL9678829 0.82 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1SMN1; SMN2POLB
SCHEMBL9668869 0.81 KMT2A (0.63) KMT2AMEN1ALDH1A1SMN1; SMN2LMNA
SCHEMBL10407053 0.81 KMT2A (0.63) KMT2AMEN1ALDH1A1SMN1; SMN2LMNA
SCHEMBL4613719 0.80 L3MBTL1 (0.46) ALDH1A1SMN1; SMN2LMNATP53HPGD
SCHEMBL12985074 0.79 KMT2A (1.00) KMT2AMEN1ALDH1A1SMN1; SMN2POLB
SCHEMBL9332380 0.79 KMT2A (0.60) KMT2AMEN1ALDH1A1SMN1; SMN2LMNA
SCHEMBL9785934 0.78 RECQL (0.43) KMT2AMEN1ALDH1A1SMN1; SMN2NPC1
SCHEMBL9332374 0.78 KMT2A (0.58) KMT2AMEN1ALDH1A1SMN1; SMN2LMNA
SCHEMBL9679602 0.78 KDM4E (0.55) KMT2AMEN1ALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1213606-B1 Radiation oncology treatment localization imaging film and method of use EASTMAN KODAK CO (US) 2004-02-18 EP disclosed
EP-1271239-A2 Portal imaging assembly with pair of asymmetric screens and method of use EASTMAN KODAK COMPANY (US) 2003-01-02 EP disclosed
EP-1271237-A1 Asymmetric contrast portal imaging assembly and method of use EASTMAN KODAK COMPANY (US) 2003-01-02 EP disclosed
EP-1271238-A2 Portal imaging assembly with neutral density filter and method of use EASTMAN KODAK COMPANY (US) 2003-01-02 EP disclosed
EP-1217433-A2 Radiation oncology treatment portal imaging film and method of use EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
EP-1213606-A2 Radiation oncology treatment localization imaging film and method of use EASTMAN KODAK COMPANY (US) 2002-06-12 EP disclosed
US-6042986-A CONFIRMING THE TARGETING OF A BEAM OF X-RADIATION OF FROM 4 TO 25 MVP USING THE PORTAL RADIOGRAPHIC ELEMENTS; X-RADIATION IS DIRECTED AT A SUBJECT CONTAINING FEATURES THAT ARE IDENTIFIABLE BY DIFFERING LEVELS OF X-RADIATION ABSORPTION EASTMAN KODAK COMPANY (US) 2000-03-28 US disclosed
US-5871892-A CONFIRMING THE TARGETING OF A BEAM OF X-RADIATION FOR THERAPY IMAGING EASTMAN KODAK COMPANY (US) 1999-02-16 US disclosed
US-5015567-A Sensitization In The Presence Of An Organic Thioether Or A Tetra-substituted Thiourea And A Triazolopyrimidine Stabilizer FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-5004669-A Printing Plates, Antistatic Agents KONICA CORPORATION (JP) 1991-04-02 US disclosed
EP-0367572-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-05-09 EP disclosed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 US disclosed
US-4680255-A Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680256-A Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680254-A Emulsions and photographic elements containing silver halide grains having hexoctamedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed