Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556011 | 1.00 | MAPT (0.50) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL8916114 | 0.81 | MAPT (0.60) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL8916104 | 0.81 | MAPT (0.60) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL6554220 | 0.81 | MAPT (0.49) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL6554226 | 0.81 | MAPT (0.49) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL27443307 | 0.79 | ATM (0.44) | MAPTALDH1A1THRBL3MBTL1MEN1 | |
| SCHEMBL4647853 | 0.75 | MAPT (0.48) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL18355121 | 0.74 | MAPT (0.51) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL18355325 | 0.74 | MAPT (0.51) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL4643328 | 0.73 | TDP1 (0.49) | MAPTLMNAALDH1A1THRBMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |