Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377005 | 0.83 | TDP1 (0.59) | TDP1MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11377008 | 0.83 | TDP1 (0.59) | TDP1MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6554370 | 0.82 | CA12 (0.42) | TDP1MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3783855 | 0.78 | PTGES2 (0.54) | MAPTALDH1A1L3MBTL1KDM4ENPC1 | |
| SCHEMBL3783857 | 0.78 | PTGES2 (0.54) | MAPTALDH1A1L3MBTL1KDM4ENPC1 | |
| SCHEMBL4619406 | 0.78 | MAPT (0.45) | MAPTALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL4619094 | 0.77 | NFE2L2 (0.53) | MAPTALDH1A1NPC1RAB9ACA12 | |
| SCHEMBL2724442 | 0.77 | NFE2L2 (0.53) | MAPTALDH1A1NPC1RAB9ACA12 | |
| SCHEMBL1194535 | 0.76 | NFE2L2 (0.49) | TDP1 | |
| SCHEMBL1194532 | 0.76 | NFE2L2 (0.49) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841415-B1 | Fine inorganic particles containing fibres and method for forming the same | JAPAN EXLAN CO LTD (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-5928785-A | ACRYLIC POLYMER WITH POLAR GROUPS SELECTED FROM SULFONIC ACID GROUP, CARBOXYL CROUP AND PHOSPHORIC ACID GROUP | JAPAN EXLAN COMPANY LIMITED (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0841415-A2 | Fine inorganic particles containing fibres and method for forming the same | JAPAN EXLAN COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |