SCHEMBL6554370

SCHEMBL6554370

Cc1cc(Cl)ccc1C=CS(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
FLT1 P17948 1/20 0.38
FLT4 P35916 1/20 0.38
KDR P35968 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
MAPK1 P28482 1/20 0.36
NFE2L2 Q16236 2/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
IDH1 O75874 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554322 0.82 TDP1 (0.52) CA12CA9TDP1ALDH1A1GAA
SCHEMBL4620075 0.80 FLT1 (0.43) FLT1FLT4KDRTDP1ALDH1A1
SCHEMBL3783855 0.79 PTGES2 (0.54) FLT1FLT4KDRNFE2L2ALDH1A1
SCHEMBL3783857 0.79 PTGES2 (0.54) FLT1FLT4KDRNFE2L2ALDH1A1
SCHEMBL5417239 0.75 MAPT (0.43) FLT1FLT4KDRTDP1ALDH1A1
SCHEMBL27739103 0.74 NFE2L2 (0.41) FLT1FLT4KDRNFE2L2ALDH1A1
SCHEMBL5420996 0.74 NFE2L2 (0.41) FLT1FLT4KDRNFE2L2ALDH1A1
SCHEMBL2724300 0.74 ALDH1A1 (0.48) CA12CA9NFE2L2ALDH1A1GAA
SCHEMBL11315447 0.74 ESR1 (0.50) ALDH1A1GAAMAPTNPC1POLB
SCHEMBL11315445 0.74 ESR1 (0.50) ALDH1A1GAAMAPTNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841415-B1 Fine inorganic particles containing fibres and method for forming the same JAPAN EXLAN CO LTD (JP) 2004-02-25 EP disclosed
US-5928785-A ACRYLIC POLYMER WITH POLAR GROUPS SELECTED FROM SULFONIC ACID GROUP, CARBOXYL CROUP AND PHOSPHORIC ACID GROUP JAPAN EXLAN COMPANY LIMITED (JP) 1999-07-27 US disclosed
EP-0841415-A2 Fine inorganic particles containing fibres and method for forming the same JAPAN EXLAN COMPANY LIMITED (JP) 1998-05-13 EP disclosed
US-5472818-A Comprising vinyl monomer, ring-opening polymerizable monomer and polyester; microspheres; toners for electrography TOYO BOSEKI KABUSHIKI KAISHA (JP) 1995-12-05 US disclosed
US-5382624-A Addition polymerization within polyester particle in dispersion, toners, electrography TOYO BOSEKI KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed