Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.62 |
| ▸ | PGR | P06401 | 15/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554278 | 0.93 | NR3C1 (0.69) | NR3C1PGRNR3C2MAPTHSD17B10 | |
| SCHEMBL6585383 | 0.85 | PGR (0.66) | NR3C1PGRNR3C2MAPTKDM4E | |
| SCHEMBL6554522 | 0.84 | PGR (0.67) | NR3C1PGRNR3C2MAPTIMPDH2 | |
| SCHEMBL5075925 | 0.83 | NR3C1 (0.54) | NR3C1PGRNR3C2MAPTIMPDH2 | |
| SCHEMBL6586035 | 0.81 | PGR (0.64) | NR3C1PGRNR3C2MAPTKDM4E | |
| SCHEMBL6006710 | 0.81 | PGR (0.56) | NR3C1PGRNR3C2MAPTIMPDH2 | |
| SCHEMBL4454877 | 0.81 | PGR (0.56) | NR3C1PGRNR3C2MAPTIMPDH2 | |
| SCHEMBL6555539 | 0.81 | PGR (0.85) | NR3C1PGRNR3C2 | |
| SCHEMBL6585839 | 0.80 | PGR (0.62) | NR3C1PGRNR3C2MAPTKDM4E | |
| SCHEMBL6556615 | 0.80 | MAPT (0.54) | NR3C1PGRNR3C2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133486-B1 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AG (DE) | 2004-12-22 | — | — | EP | claimed |
| CN-1171883-C | Nonsteroidal antiinflammatories | ���ֹɷݹ�˾ | 2004-10-20 | — | — | CN | claimed |
| CN-1334809-A | Non-steroidal anti-inflammatory drugs | SCHERING AG (DE) | 2002-02-06 | — | — | CN | claimed |
| US-6323199-B1 | AROMATIC HETEROCYCLIC HYDROXY AMINES OR AMIDES FOR TREATMENT OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | claimed |
| EP-1133486-B1 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| CN-1171883-C | Nonsteroidal antiinflammatories | ���ֹɷݹ�˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1334809-A | Non-steroidal anti-inflammatory drugs | SCHERING AG (DE) | 2002-02-06 | — | — | CN | disclosed |
| US-6323199-B1 | AROMATIC HETEROCYCLIC HYDROXY AMINES OR AMIDES FOR TREATMENT OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | disclosed |
| EP-1133486-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032584-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |