Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389879 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL7304791 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL11585903 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5233459 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5233467 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL20061841 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL7398961 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL24648736 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL15244828 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL4994907 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389111-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM i PAECILOMYCES SP. /i (TOCHU-KASO) J300 | Republic of Korea (KR) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002080921-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM PAECILOMYCES SP. (TOCHU-KASO) J300 | REPUBLIC OF KOREA (KR) | 2002-10-17 | — | — | WO | disclosed |