Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389879 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL6554333 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL24648736 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL15244828 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL4994907 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL20061874 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5873415 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL31421469 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5873425 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL12966021 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |