Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.52 |
| ▸ | PGR | P06401 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692378 | 0.89 | NR3C1 (0.50) | NR3C1PGRNR3C2AR | |
| SCHEMBL6689551 | 0.85 | NR3C1 (0.52) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL4025539 | 0.82 | CA12 (0.55) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL17307543 | 0.82 | CA12 (0.48) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL4163146 | 0.80 | NR3C1 (0.53) | NR3C1PGRNR3C2AR | |
| SCHEMBL6688760 | 0.80 | NR3C1 (0.60) | NR3C1PGRNR3C2AR | |
| SCHEMBL4176230 | 0.79 | NR3C1 (0.46) | NR3C1PGRNR3C2AR | |
| SCHEMBL4278672 | 0.79 | NR3C1 (0.52) | NR3C1PGRNR3C2AR | |
| SCHEMBL4167078 | 0.79 | NR3C1 (0.47) | NR3C1PGRNR3C2AR | |
| SCHEMBL4173498 | 0.79 | NR3C1 (0.49) | NR3C1PGRNR3C2ARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133486-B1 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| US-6323199-B1 | AROMATIC HETEROCYCLIC HYDROXY AMINES OR AMIDES FOR TREATMENT OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | disclosed |
| EP-1133486-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032584-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |