Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | WDR5 | P61964 | 1/20 | 0.61 |
| ▸ | ATIC | P31939 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474197 | 1.00 | CES1 (1.00) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL29561444 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL29549661 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL28396921 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL18395077 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL29118838 | 0.90 | PRMT1 (0.90) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL2136408 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL96121 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL6302309 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL31689478 | 0.90 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104353-B1 | HEAT SENSITIVE RECORD MATERIAL | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| US-4482905-A | FLUORAN, BENZENESULFONAMIDE, ACID, BINDER | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | claimed |
| EP-0104353-A2 | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-04-04 | — | — | EP | claimed |
| CN-111170905-B | Synthetic method of sulfonamide compound | 台州学院 | 2022-04-29 | — | — | CN | disclosed |
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| WO-2002078970-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-5817709-A | CURING AGENTS; CROSSLINKING | CYTEC TECHNOLOGY CORP. (US) | 1998-10-06 | — | — | US | disclosed |
| US-5648434-A | AMINOPLAST CROSSLINKING AGENTS AND CATALYSTS | CYTEC TECHNOLOGY CORP. (US) | 1997-07-15 | — | — | US | disclosed |
| US-5643682-A | AMINOPLAST CROSSLINKING AGENTS AND CATALYSTS | CYTEC TECHNOLOGY CORP. (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0453730-B1 | Sulfonimide catalysts for coatings | CYTEC TECH CORP (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0509138-B1 | Sulfonimide catalysts for coatings | CYTEC TECH CORP (US) | 1995-08-02 | — | — | EP | disclosed |
| US-5256493-A | Crosslinking agent for heat curable coatings | CYTEC TECHNOLOGY CORP. | 1993-10-26 | — | — | US | disclosed |
| EP-0509138-A2 | Sulfonimide catalysts for coatings | CYTEC TECHNOLOGY CORP. (US) | 1992-10-21 | — | — | EP | disclosed |
| EP-0453730-A1 | Sulfonimide catalysts for coatings | CYTEC TECHNOLOGY CORP. (US) | 1991-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | CES1 275/4885ALDH1A1 453/4885PRMT1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.